{"id":8704,"date":"2025-02-03T10:20:00","date_gmt":"2025-02-03T09:20:00","guid":{"rendered":"https:\/\/fhu-premimpact.org\/?post_type=publication&#038;p=8704"},"modified":"2025-09-01T10:23:42","modified_gmt":"2025-09-01T08:23:42","slug":"maternal-prepregnancy-obesity-and-offspring-intelligence-quotient-at-5-years-a-multicohort-analysis","status":"publish","type":"publication","link":"https:\/\/fhu-premimpact.org\/en\/publications\/maternal-prepregnancy-obesity-and-offspring-intelligence-quotient-at-5-years-a-multicohort-analysis\/","title":{"rendered":"Maternal Prepregnancy Obesity and Offspring Intelligence Quotient at 5\u2009Years: A Multicohort Analysis."},"content":{"rendered":"\n<h2 class=\"wp-block-heading\">ABSTRACT<\/h2>\n\n\n\n<p><br>Background: The relationship between maternal obesity and childhood cognitive development remains unclear. Prior stu<br>ies did not adjust for important confounders, and preterm infants are a developmentally distinct group that remains scarcely<br>examined.<br>Objectives: To determine whether maternal prepregnancy body mass index (BMI) is associated with offspring intelligence quo-<br>tient (IQ) up to 5 years and whether this relationship varies with gestational age.<br>Methods: Data from two French birth cohorts, EDEN (all gestational ages) and EPIPAGE-2 (preterm children born between 24<br>and 34 weeks of gestation), were used for this study. Maternal prepregnancy weight and height were used to calculate prepreg-<br>nancy BMI. The Wechsler Preschool and Primary Scale of Intelligence was used to assess child IQ around 5 years. Multivariable<br>models were adjusted for confounders, including socioeconomic status and paternal BMI.<br>Results: Analytical cohorts included 1100 children from EDEN and 2629 from EPIPAGE-2. Lower intellectual functioning<br>(full-scale IQ &lt; 85) was observed in 8.1% of children in EDEN and 19.6% in EPIPAGE-2. The prevalence of maternal obesity was<br>13.6% (EDEN) and 21.3% (EPIPAGE-2) among children with lower intellectual functioning compared to 8.9% (EDEN) and 12.9%<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Paediatr Perinat Epidemiol. 2025 Feb;39(2):162-174<\/p>\n","protected":false},"featured_media":0,"template":"","class_list":["post-8704","publication","type-publication","status-publish","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.2 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Maternal Prepregnancy Obesity and Offspring Intelligence Quotient at 5\u2009Years: A Multicohort Analysis. - FHU Prem&#039;IMPACT<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/fhu-premimpact.org\/en\/publications\/maternal-prepregnancy-obesity-and-offspring-intelligence-quotient-at-5-years-a-multicohort-analysis\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Maternal Prepregnancy Obesity and Offspring Intelligence Quotient at 5\u2009Years: A Multicohort Analysis. - 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