{"id":8545,"date":"2025-04-01T14:41:00","date_gmt":"2025-04-01T12:41:00","guid":{"rendered":"https:\/\/fhu-premimpact.org\/?post_type=publication&#038;p=8545"},"modified":"2025-06-30T14:56:03","modified_gmt":"2025-06-30T12:56:03","slug":"antepartum-severe-maternal-morbidity-in-women-with-preterm-delivery-a-national-cohort-study","status":"publish","type":"publication","link":"https:\/\/fhu-premimpact.org\/en\/publications\/antepartum-severe-maternal-morbidity-in-women-with-preterm-delivery-a-national-cohort-study\/","title":{"rendered":"Antepartum severe maternal morbidity in women with preterm delivery : A national cohort study"},"content":{"rendered":"\n<h3 class=\"wp-block-heading\">Abstract <\/h3>\n\n\n\n<p><strong>Introduction<\/strong>: the literature extensively documents neonatal and paediatric outcomes related to preterm delivery,<br>but maternal health in this circumtances remains underexplored.<br>This study aimed to identify women with antepartum severe maternal morbidity (SMM) among those delivering<br>preterm and explore whether they delivered in hospitals with risk-appropriate maternal care facilities.<br>Material and methods: Women giving birth at 22\u201334 weeks of gestation were identified from the French national<br>prospective EPIPAGE-2 cohort study in 2011; terminations of pregnancy for fetal congenital malformations were<br>excluded. Antepartum SMM was defined as a composite outcome of severe maternal morbid events preceding<br>labour onset or the delivery decision. We described antepartum SMM and compared women with and without<br>SMM regarding the characteristics of the hospital of delivery.<br><strong>Results <\/strong>: among 5,690 women included, 886 (16.0 %, 95 % CI, 14.7, 17.0) experienced antepartum SMM, pri-<br>marily due to severe pregnancy-related hypertensive disorders or major obstetric bleeding. Women with ante-<br>partum SMM were more likely to deliver in level III maternity units (level of neonatal care) compared with<br>women without antepartum SMM (68.0 % vs 59.3 %, P &lt; 0.001). However, 18.3 % of women with antepartum<br>SMM delivered in hospitals without an onsite adult critical care unit, a proportion not significantly different from<br>those without SMM (22.0 %, P = 0.23).<br><strong>Conclusions :<\/strong> antepartum SMM affected one in six women delivering at 22\u201334 weeks\u2019 gestation. Many did not<br>deliver in hospitals equipped with adult critical care unit. Delivery locations for women with SMM at risk of<br>preterm birth should address the needs of both the mother and the newborn.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Eur J Obstet Gynecol Reprod Biol. 2025 Apr; 307:98-104.<\/p>\n","protected":false},"featured_media":0,"template":"","class_list":["post-8545","publication","type-publication","status-publish","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.2 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Antepartum severe maternal morbidity in women with preterm delivery : A national cohort study - FHU Prem&#039;IMPACT<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/fhu-premimpact.org\/en\/publications\/antepartum-severe-maternal-morbidity-in-women-with-preterm-delivery-a-national-cohort-study\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Antepartum severe maternal morbidity in women with preterm delivery : A national cohort study - FHU Prem&#039;IMPACT\" \/>\n<meta property=\"og:description\" content=\"Eur J Obstet Gynecol Reprod Biol. 2025 Apr; 307:98-104.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/fhu-premimpact.org\/en\/publications\/antepartum-severe-maternal-morbidity-in-women-with-preterm-delivery-a-national-cohort-study\/\" \/>\n<meta property=\"og:site_name\" content=\"FHU Prem&#039;IMPACT\" \/>\n<meta property=\"article:modified_time\" content=\"2025-06-30T12:56:03+00:00\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"2 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/fhu-premimpact.org\/en\/publications\/antepartum-severe-maternal-morbidity-in-women-with-preterm-delivery-a-national-cohort-study\/\",\"url\":\"https:\/\/fhu-premimpact.org\/en\/publications\/antepartum-severe-maternal-morbidity-in-women-with-preterm-delivery-a-national-cohort-study\/\",\"name\":\"Antepartum severe maternal morbidity in women with preterm delivery : A national cohort study - FHU Prem&#039;IMPACT\",\"isPartOf\":{\"@id\":\"https:\/\/fhu-premimpact.org\/en\/#website\"},\"datePublished\":\"2025-04-01T12:41:00+00:00\",\"dateModified\":\"2025-06-30T12:56:03+00:00\",\"breadcrumb\":{\"@id\":\"https:\/\/fhu-premimpact.org\/en\/publications\/antepartum-severe-maternal-morbidity-in-women-with-preterm-delivery-a-national-cohort-study\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/fhu-premimpact.org\/en\/publications\/antepartum-severe-maternal-morbidity-in-women-with-preterm-delivery-a-national-cohort-study\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/fhu-premimpact.org\/en\/publications\/antepartum-severe-maternal-morbidity-in-women-with-preterm-delivery-a-national-cohort-study\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Accueil\",\"item\":\"https:\/\/fhu-premimpact.org\/en\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Publications\",\"item\":\"https:\/\/fhu-premimpact.org\/en\/publications\/\"},{\"@type\":\"ListItem\",\"position\":3,\"name\":\"Antepartum severe maternal morbidity in women with preterm delivery : A national cohort study\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/fhu-premimpact.org\/en\/#website\",\"url\":\"https:\/\/fhu-premimpact.org\/en\/\",\"name\":\"FHU PREM'IMPACT\",\"description\":\"Perinatal inflammation and prematurity\",\"publisher\":{\"@id\":\"https:\/\/fhu-premimpact.org\/en\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/fhu-premimpact.org\/en\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Organization\",\"@id\":\"https:\/\/fhu-premimpact.org\/en\/#organization\",\"name\":\"FHU PREM'IMPACT\",\"url\":\"https:\/\/fhu-premimpact.org\/en\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/fhu-premimpact.org\/en\/#\/schema\/logo\/image\/\",\"url\":\"https:\/\/fhu-premimpact.org\/wp-content\/uploads\/2025\/03\/logo-grand-centre-fhupremimpact.jpg\",\"contentUrl\":\"https:\/\/fhu-premimpact.org\/wp-content\/uploads\/2025\/03\/logo-grand-centre-fhupremimpact.jpg\",\"width\":1280,\"height\":720,\"caption\":\"FHU PREM'IMPACT\"},\"image\":{\"@id\":\"https:\/\/fhu-premimpact.org\/en\/#\/schema\/logo\/image\/\"},\"sameAs\":[\"https:\/\/www.instagram.com\/fhupremimpact\/\",\"https:\/\/www.linkedin.com\/in\/fhu-prem-impact-ap-hp-inserm-universit-paris-cit-70b911253\/\"]}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Antepartum severe maternal morbidity in women with preterm delivery : A national cohort study - FHU Prem&#039;IMPACT","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/fhu-premimpact.org\/en\/publications\/antepartum-severe-maternal-morbidity-in-women-with-preterm-delivery-a-national-cohort-study\/","og_locale":"en_US","og_type":"article","og_title":"Antepartum severe maternal morbidity in women with preterm delivery : A national cohort study - FHU Prem&#039;IMPACT","og_description":"Eur J Obstet Gynecol Reprod Biol. 2025 Apr; 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