{"id":7804,"date":"2024-03-16T13:42:02","date_gmt":"2024-03-16T12:42:02","guid":{"rendered":"https:\/\/fhu-premimpact.org\/?post_type=publication&#038;p=7804"},"modified":"2025-03-24T13:45:43","modified_gmt":"2025-03-24T12:45:43","slug":"maternal-and-neonatal-outcomes-of-french-prospective-multicenter-cohort-study-covipreg-during-the-first-two-covid-19-waves","status":"publish","type":"publication","link":"https:\/\/fhu-premimpact.org\/en\/publications\/maternal-and-neonatal-outcomes-of-french-prospective-multicenter-cohort-study-covipreg-during-the-first-two-covid-19-waves\/","title":{"rendered":"Maternal and neonatal outcomes of French prospective multicenter cohort study COVIPREG during the first two COVID-19 waves"},"content":{"rendered":"\n<h4 class=\"wp-block-heading\">Abstract<\/h4>\n\n\n\n<p><strong>Background:<\/strong> SARS-CoV-2 infection on pregnant women was the subject of many questions since the COVID-19 pandemic.<\/p>\n\n\n\n<p><strong>Methods:<\/strong> We aim to assess maternal and neonatal outcomes of SARS-CoV-2 infection contracted during 2nd and 3rd trimesters of pregnancy during the first two COVID-19 waves across a prospective French multicenter cohort study. Patients were included between April 2020 and January 2021 in 10 maternity hospitals in Paris area with two groups (i) pregnant women with a positive SARS-CoV-2 nasopharyngeal RT-PCR between [14WG; 37WG[(symptomatic infection), (ii) pregnant women with a negative serology (or equivocal) at delivery and without a positive SARS-CoV-2 nasopharyngeal RT-PCR at any time during pregnancy (G2 group) MAIN FINDINGS: 2410 pregnant women were included, of whom 310 had a positive SARS-CoV-2 nasopharyngeal RT-PCR and 217 between [14WG; 37WG[. Most infections occurred between 28 and 37 weeks of gestation (56 %). Most patients could be managed as outpatients, while 23 % had to be hospitalized. Among women with a positive RT-PCR, multiparous women were over-represented (OR = 2.45[1.52;3.87]); were more likely to deliver before 37 weeks of gestation (OR = 2.19[1.44;3.24]) and overall cesarean deliveries were significantly increased (OR = 1.53[1.09;2.13]).<\/p>\n\n\n\n<p><strong>Conclusions:<\/strong> This study highlights the maternal, obstetrical, and neonatal burden associated with SARS-CoV-2 infections during the first two pandemic waves before availability of vaccines.<\/p>\n","protected":false},"excerpt":{"rendered":"<p> J Gynecol Obstet Hum Reprod. 2024 Jun;53(6):102764<\/p>\n","protected":false},"featured_media":0,"template":"","class_list":["post-7804","publication","type-publication","status-publish","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.2 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Maternal and neonatal outcomes of French prospective multicenter cohort study COVIPREG during the first two COVID-19 waves - FHU Prem&#039;IMPACT<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/fhu-premimpact.org\/en\/publications\/maternal-and-neonatal-outcomes-of-french-prospective-multicenter-cohort-study-covipreg-during-the-first-two-covid-19-waves\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Maternal and neonatal outcomes of French prospective multicenter cohort study COVIPREG during the first two COVID-19 waves - FHU Prem&#039;IMPACT\" \/>\n<meta property=\"og:description\" content=\"J Gynecol Obstet Hum Reprod. 2024 Jun;53(6):102764\" \/>\n<meta property=\"og:url\" content=\"https:\/\/fhu-premimpact.org\/en\/publications\/maternal-and-neonatal-outcomes-of-french-prospective-multicenter-cohort-study-covipreg-during-the-first-two-covid-19-waves\/\" \/>\n<meta property=\"og:site_name\" content=\"FHU Prem&#039;IMPACT\" \/>\n<meta property=\"article:modified_time\" content=\"2025-03-24T12:45:43+00:00\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"2 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/fhu-premimpact.org\/en\/publications\/maternal-and-neonatal-outcomes-of-french-prospective-multicenter-cohort-study-covipreg-during-the-first-two-covid-19-waves\/\",\"url\":\"https:\/\/fhu-premimpact.org\/en\/publications\/maternal-and-neonatal-outcomes-of-french-prospective-multicenter-cohort-study-covipreg-during-the-first-two-covid-19-waves\/\",\"name\":\"Maternal and neonatal outcomes of French prospective multicenter cohort study COVIPREG during the first two COVID-19 waves - 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