{"id":7567,"date":"2024-04-15T17:55:14","date_gmt":"2024-04-15T15:55:14","guid":{"rendered":"https:\/\/fhu-premimpact.org\/?post_type=publication&#038;p=7567"},"modified":"2024-05-14T18:01:48","modified_gmt":"2024-05-14T16:01:48","slug":"systematic-culture-of-central-catheters-and-infections-related-to-catheters-in-a-neonatal-intensive-care-unit-an-observational-study","status":"publish","type":"publication","link":"https:\/\/fhu-premimpact.org\/en\/publications\/systematic-culture-of-central-catheters-and-infections-related-to-catheters-in-a-neonatal-intensive-care-unit-an-observational-study\/","title":{"rendered":"Systematic culture of central catheters and infections related to catheters in a neonatal intensive care unit: an observational study"},"content":{"rendered":"\n<h4 class=\"wp-block-heading\">Abstract<\/h4>\n\n\n\n<p>Systematic culture of the tip of central lines is performed in many neonatal intensive care units (NICUs) to guide any subsequent antibiotic therapy. The clinical relevance of this procedure is debated, given the significant bacterial contamination during its removal. We aimed to describe infections related to catheters and assess the usefulness of central catheter systematic cultures for probabilistic antibiotic therapy in cases of suspicion of catheter-related infections in a NICU. A retrospective study in a NICU included all newborn patients hospitalized with a central catheter, between January 2018, and June 2019. The main outcome measures were bacterial catheter colonization, catheter-related infection rate, and simulation-based approach to antibiotic prescription. Three hundred and seventy-five newborns, with 634 central catheters were included. There were 273 (43%) catheters that were colonized by at least one microorganism. There were 183 cases of suspected sepsis, with 31 infections definitively related to the catheter. In our simulation antibiotic prescription approach, there was no significant difference in terms of the efficacy toward the microorganism(s) involved between the probabilistic antibiotic therapies proposed by the experts and those ultimately prescribed. Performing a catheter culture only if catheter-related infection is suspected could be an alternative to routine screening<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Sci Rep. 2024 Apr 15;14(1):8647. doi: 10.1038<\/p>\n","protected":false},"featured_media":0,"template":"","class_list":["post-7567","publication","type-publication","status-publish","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.2 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Systematic culture of central catheters and infections related to catheters in a neonatal intensive care unit: an observational study - FHU Prem&#039;IMPACT<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/fhu-premimpact.org\/en\/publications\/systematic-culture-of-central-catheters-and-infections-related-to-catheters-in-a-neonatal-intensive-care-unit-an-observational-study\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Systematic culture of central catheters and infections related to catheters in a neonatal intensive care unit: an observational study - FHU Prem&#039;IMPACT\" \/>\n<meta property=\"og:description\" content=\"Sci Rep. 2024 Apr 15;14(1):8647. doi: 10.1038\" \/>\n<meta property=\"og:url\" content=\"https:\/\/fhu-premimpact.org\/en\/publications\/systematic-culture-of-central-catheters-and-infections-related-to-catheters-in-a-neonatal-intensive-care-unit-an-observational-study\/\" \/>\n<meta property=\"og:site_name\" content=\"FHU Prem&#039;IMPACT\" \/>\n<meta property=\"article:modified_time\" content=\"2024-05-14T16:01:48+00:00\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"2 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/fhu-premimpact.org\/en\/publications\/systematic-culture-of-central-catheters-and-infections-related-to-catheters-in-a-neonatal-intensive-care-unit-an-observational-study\/\",\"url\":\"https:\/\/fhu-premimpact.org\/en\/publications\/systematic-culture-of-central-catheters-and-infections-related-to-catheters-in-a-neonatal-intensive-care-unit-an-observational-study\/\",\"name\":\"Systematic culture of central catheters and infections related to catheters in a neonatal intensive care unit: an observational study - FHU Prem&#039;IMPACT\",\"isPartOf\":{\"@id\":\"https:\/\/fhu-premimpact.org\/en\/#website\"},\"datePublished\":\"2024-04-15T15:55:14+00:00\",\"dateModified\":\"2024-05-14T16:01:48+00:00\",\"breadcrumb\":{\"@id\":\"https:\/\/fhu-premimpact.org\/en\/publications\/systematic-culture-of-central-catheters-and-infections-related-to-catheters-in-a-neonatal-intensive-care-unit-an-observational-study\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/fhu-premimpact.org\/en\/publications\/systematic-culture-of-central-catheters-and-infections-related-to-catheters-in-a-neonatal-intensive-care-unit-an-observational-study\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/fhu-premimpact.org\/en\/publications\/systematic-culture-of-central-catheters-and-infections-related-to-catheters-in-a-neonatal-intensive-care-unit-an-observational-study\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Accueil\",\"item\":\"https:\/\/fhu-premimpact.org\/en\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Publications\",\"item\":\"https:\/\/fhu-premimpact.org\/en\/publications\/\"},{\"@type\":\"ListItem\",\"position\":3,\"name\":\"Systematic culture of central catheters and infections related to catheters in a neonatal intensive care unit: an observational study\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/fhu-premimpact.org\/en\/#website\",\"url\":\"https:\/\/fhu-premimpact.org\/en\/\",\"name\":\"FHU PREM'IMPACT\",\"description\":\"Perinatal inflammation and prematurity\",\"publisher\":{\"@id\":\"https:\/\/fhu-premimpact.org\/en\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/fhu-premimpact.org\/en\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Organization\",\"@id\":\"https:\/\/fhu-premimpact.org\/en\/#organization\",\"name\":\"FHU PREM'IMPACT\",\"url\":\"https:\/\/fhu-premimpact.org\/en\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/fhu-premimpact.org\/en\/#\/schema\/logo\/image\/\",\"url\":\"https:\/\/fhu-premimpact.org\/wp-content\/uploads\/2025\/03\/logo-grand-centre-fhupremimpact.jpg\",\"contentUrl\":\"https:\/\/fhu-premimpact.org\/wp-content\/uploads\/2025\/03\/logo-grand-centre-fhupremimpact.jpg\",\"width\":1280,\"height\":720,\"caption\":\"FHU PREM'IMPACT\"},\"image\":{\"@id\":\"https:\/\/fhu-premimpact.org\/en\/#\/schema\/logo\/image\/\"},\"sameAs\":[\"https:\/\/www.instagram.com\/fhupremimpact\/\",\"https:\/\/www.linkedin.com\/in\/fhu-prem-impact-ap-hp-inserm-universit-paris-cit-70b911253\/\"]}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Systematic culture of central catheters and infections related to catheters in a neonatal intensive care unit: an observational study - FHU Prem&#039;IMPACT","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/fhu-premimpact.org\/en\/publications\/systematic-culture-of-central-catheters-and-infections-related-to-catheters-in-a-neonatal-intensive-care-unit-an-observational-study\/","og_locale":"en_US","og_type":"article","og_title":"Systematic culture of central catheters and infections related to catheters in a neonatal intensive care unit: an observational study - FHU Prem&#039;IMPACT","og_description":"Sci Rep. 2024 Apr 15;14(1):8647. doi: 10.1038","og_url":"https:\/\/fhu-premimpact.org\/en\/publications\/systematic-culture-of-central-catheters-and-infections-related-to-catheters-in-a-neonatal-intensive-care-unit-an-observational-study\/","og_site_name":"FHU Prem&#039;IMPACT","article_modified_time":"2024-05-14T16:01:48+00:00","twitter_card":"summary_large_image","twitter_misc":{"Est. reading time":"2 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/fhu-premimpact.org\/en\/publications\/systematic-culture-of-central-catheters-and-infections-related-to-catheters-in-a-neonatal-intensive-care-unit-an-observational-study\/","url":"https:\/\/fhu-premimpact.org\/en\/publications\/systematic-culture-of-central-catheters-and-infections-related-to-catheters-in-a-neonatal-intensive-care-unit-an-observational-study\/","name":"Systematic culture of central catheters and infections related to catheters in a neonatal intensive care unit: an observational study - FHU Prem&#039;IMPACT","isPartOf":{"@id":"https:\/\/fhu-premimpact.org\/en\/#website"},"datePublished":"2024-04-15T15:55:14+00:00","dateModified":"2024-05-14T16:01:48+00:00","breadcrumb":{"@id":"https:\/\/fhu-premimpact.org\/en\/publications\/systematic-culture-of-central-catheters-and-infections-related-to-catheters-in-a-neonatal-intensive-care-unit-an-observational-study\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/fhu-premimpact.org\/en\/publications\/systematic-culture-of-central-catheters-and-infections-related-to-catheters-in-a-neonatal-intensive-care-unit-an-observational-study\/"]}]},{"@type":"BreadcrumbList","@id":"https:\/\/fhu-premimpact.org\/en\/publications\/systematic-culture-of-central-catheters-and-infections-related-to-catheters-in-a-neonatal-intensive-care-unit-an-observational-study\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Accueil","item":"https:\/\/fhu-premimpact.org\/en\/"},{"@type":"ListItem","position":2,"name":"Publications","item":"https:\/\/fhu-premimpact.org\/en\/publications\/"},{"@type":"ListItem","position":3,"name":"Systematic culture of central catheters and infections related to catheters in a neonatal intensive care unit: an observational study"}]},{"@type":"WebSite","@id":"https:\/\/fhu-premimpact.org\/en\/#website","url":"https:\/\/fhu-premimpact.org\/en\/","name":"FHU PREM'IMPACT","description":"Perinatal inflammation and prematurity","publisher":{"@id":"https:\/\/fhu-premimpact.org\/en\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/fhu-premimpact.org\/en\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"},{"@type":"Organization","@id":"https:\/\/fhu-premimpact.org\/en\/#organization","name":"FHU PREM'IMPACT","url":"https:\/\/fhu-premimpact.org\/en\/","logo":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/fhu-premimpact.org\/en\/#\/schema\/logo\/image\/","url":"https:\/\/fhu-premimpact.org\/wp-content\/uploads\/2025\/03\/logo-grand-centre-fhupremimpact.jpg","contentUrl":"https:\/\/fhu-premimpact.org\/wp-content\/uploads\/2025\/03\/logo-grand-centre-fhupremimpact.jpg","width":1280,"height":720,"caption":"FHU PREM'IMPACT"},"image":{"@id":"https:\/\/fhu-premimpact.org\/en\/#\/schema\/logo\/image\/"},"sameAs":["https:\/\/www.instagram.com\/fhupremimpact\/","https:\/\/www.linkedin.com\/in\/fhu-prem-impact-ap-hp-inserm-universit-paris-cit-70b911253\/"]}]}},"uagb_featured_image_src":{"full":false,"thumbnail":false,"medium":false,"medium_large":false,"large":false,"1536x1536":false,"2048x2048":false,"post-thumbnail":false,"twentytwenty-fullscreen":false},"uagb_author_info":{"display_name":"Laurence Lecomte","author_link":"https:\/\/fhu-premimpact.org\/en\/author\/"},"uagb_comment_info":0,"uagb_excerpt":"Sci Rep. 2024 Apr 15;14(1):8647. doi: 10.1038","_links":{"self":[{"href":"https:\/\/fhu-premimpact.org\/en\/wp-json\/wp\/v2\/publication\/7567","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/fhu-premimpact.org\/en\/wp-json\/wp\/v2\/publication"}],"about":[{"href":"https:\/\/fhu-premimpact.org\/en\/wp-json\/wp\/v2\/types\/publication"}],"wp:attachment":[{"href":"https:\/\/fhu-premimpact.org\/en\/wp-json\/wp\/v2\/media?parent=7567"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}