{"id":4075,"date":"2021-05-01T14:56:00","date_gmt":"2021-05-01T12:56:00","guid":{"rendered":"https:\/\/fhu-premimpact.org\/?post_type=publication&#038;p=4075"},"modified":"2021-07-22T14:58:38","modified_gmt":"2021-07-22T12:58:38","slug":"contribution-of-prepregnancy-obesity-to-racial-and-ethnic-disparities-in-severe-maternal-morbidity","status":"publish","type":"publication","link":"https:\/\/fhu-premimpact.org\/en\/publications\/contribution-of-prepregnancy-obesity-to-racial-and-ethnic-disparities-in-severe-maternal-morbidity\/","title":{"rendered":"Contribution of Prepregnancy Obesity to Racial and Ethnic Disparities in Severe Maternal Morbidity."},"content":{"rendered":"\n<h4 class=\"wp-block-heading\">Abstract<\/h4>\n\n\n\n<p><strong>Objective:&nbsp;<\/strong>To evaluate the role of prepregnancy obesity as a mediator in the association between race-ethnicity and severe maternal morbidity.<\/p>\n\n\n\n<p><strong>Methods:&nbsp;<\/strong>We conducted an analysis on a population-based retrospective cohort study using 2010-2014 birth records linked with hospital discharge data in New York City. A multivariable logistic regression mediation model on a subgroup of the sample consisting of normal-weight and obese women (n=409,021) calculated the mediation effect of obesity in the association between maternal race-ethnicity and severe maternal morbidity, and the residual effect not mediated by obesity. A sensitivity analysis was conducted excluding the severe maternal morbidity cases due to blood transfusion.<\/p>\n\n\n\n<p><strong>Results:&nbsp;<\/strong>Among 591,455 live births, we identified 15,158 cases of severe maternal morbidity (256.3\/10,000 deliveries). The severe maternal morbidity rate among obese women was higher than that of normal-weight women (342 vs 216\/10,000 deliveries). Black women had a severe maternal morbidity rate nearly three times higher than White women (420 vs 146\/10,000 deliveries) and the severe maternal morbidity rate among Latinas was nearly twice that of White women (285\/10,000 deliveries). Among women with normal or obese body mass index (BMI) only (n=409,021), Black race was strongly associated with severe maternal morbidity (adjusted odds ratio [aOR] 3.02, 95% CI 2.88-3.17) but the obesity-mediated effect represented only 3.2% of the total association (aOR 1.03, 95% CI 1.02-1.05). Latina ethnicity was also associated with severe maternal morbidity (aOR 2.01, 95% CI 1.90-2.12) and the obesity-mediated effect was similarly small: 3.4% of the total association (aOR 1.02, 95% CI 1.01-1.03). In a sensitivity analysis excluding blood transfusion, severe maternal morbidity cases found a higher mediation effect of obesity in the association with Black race and Latina ethnicity (15.3% and 15.2% of the total association, respectively).<\/p>\n","protected":false},"excerpt":{"rendered":"<p> Obstet Gynecol. 2021 May 1;137(5):864-872. doi: 10.1097\/AOG.0000000000004356. PMID: 33831920.<\/p>\n","protected":false},"featured_media":0,"template":"","class_list":["post-4075","publication","type-publication","status-publish","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.2 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Contribution of Prepregnancy Obesity to Racial and Ethnic Disparities in Severe Maternal Morbidity. - FHU Prem&#039;IMPACT<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/fhu-premimpact.org\/en\/publications\/contribution-of-prepregnancy-obesity-to-racial-and-ethnic-disparities-in-severe-maternal-morbidity\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Contribution of Prepregnancy Obesity to Racial and Ethnic Disparities in Severe Maternal Morbidity. - FHU Prem&#039;IMPACT\" \/>\n<meta property=\"og:description\" content=\"Obstet Gynecol. 2021 May 1;137(5):864-872. doi: 10.1097\/AOG.0000000000004356. 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